Package: posologyr
Title: Individual Dose Optimization using Population Pharmacokinetics
Version: 1.2.8.999
Authors@R: c(
    person("Cyril","Leven",role = c("aut", "cre","cph"),
           email = "cyril.leven@chu-brest.fr",
           comment = c(ORCID = "0000-0002-0697-4370")),
    person("Matthew","Fidler",role = c("ctb"),
           email="matthew.fidler@gmail.com",
           comment = c(ORCID = "0000-0001-8538-6691")),
    person("Emmanuelle","Comets",role = c("ctb")),
    person("Audrey","Lavenu",role = c("ctb")),
    person("Marc","Lavielle",role = c("ctb"))
    )
Description: Personalize drug regimens using individual pharmacokinetic
        (PK) and pharmacokinetic-pharmacodynamic (PK-PD) profiles. By
        combining therapeutic drug monitoring (TDM) data with a
        population model, 'posologyr' offers accurate posterior
        estimates and helps compute optimal individualized dosing
        regimens. The empirical Bayes estimates are computed following
        the method described by Kang et al. (2012)
        <doi:10.4196/kjpp.2012.16.2.97>.
License: AGPL-3
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.3
Depends: R (>= 3.5.0)
Imports: rxode2, stats, mvtnorm, data.table
Suggests: lotri, rmarkdown, testthat (>= 3.0.0), ggplot2, magrittr,
        tidyr
URL: https://levenc.github.io/posologyr/,
        https://github.com/levenc/posologyr
BugReports: https://github.com/levenc/posologyr/issues
Config/testthat/edition: 3
Config/pak/sysreqs: cmake make
Repository: https://levenc.r-universe.dev
Date/Publication: 2026-04-10 12:41:53 UTC
RemoteUrl: https://github.com/levenc/posologyr
RemoteRef: HEAD
RemoteSha: 9839df6e6ef67f9f3af079853efb2b84bf1bc99c
NeedsCompilation: no
Packaged: 2026-10-14 11:16:04 UTC; root
Author: Cyril Leven [aut, cre, cph] (ORCID:
    <https://orcid.org/0000-0002-0697-4370>),
  Matthew Fidler [ctb] (ORCID: <https://orcid.org/0000-0001-8538-6691>),
  Emmanuelle Comets [ctb],
  Audrey Lavenu [ctb],
  Marc Lavielle [ctb]
Maintainer: Cyril Leven <cyril.leven@chu-brest.fr>